← Issue №10/ week of Sep 6, 2026/Endoscopy

Endoscopic Ultrasound-Guided Transluminal Drainage of Walled-Off Necrosis Using Naso-Cystic Drain With Metal Stent Versus Metal Stent Alone: A Randomized Controlled Pilot Study.

From GI Signals issue №10: what this paper found, what it changes, and where it sits against the current standard of care, reviewed by Simon Mathews, MD.

Endoscopy rct · n=40 · Sep 1, 2026 · Pancreas · IF 1.9

Endoscopic Ultrasound-Guided Transluminal Drainage of Walled-Off Necrosis Using Naso-Cystic Drain With Metal Stent Versus Metal Stent Alone: A Randomized Controlled Pilot Study.

New evidenceEUSendoscopy quality
Clinical takeawayDo not routinely add nasocystic drainage to EUS-guided LAMS for WON; LAMS alone is non-inferior and may shorten hospitalization. However, these findings are exploratory and require confirmation in larger trials.
What it foundAdding nasocystic drainage (NCD) to EUS-guided LAMS for walled-off necrosis (WON) did not improve clinical success compared to LAMS alone (55% vs 45% at day 3, P=0.527) and prolonged median hospital stay (specific duration not provided, P=0.038).
ContextChallenges the uncertain role of NCD as an adjunct to LAMS, suggesting it adds no benefit in WON drainage. Findings are exploratory due to small sample size and baseline imbalance.
No standard claimed for this paper

Every paper is compared to the standard governing its question. This one is not: either no standard in the corpus matches it, or the comparison did not hold up on review and was withdrawn rather than published unverified. Both are logged.

Kar N … Gautam V · Pancreas · IF 1.9 · PubMed ↗Permalink
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